Gastrin Monoclonal antibody

Gastrin Monoclonal Antibody for IHC,ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

IHC, IF,ELISA

Conjugate

Unconjugated

Publications

1

CloneNo.

7G9C3

Cat no : 60346-1-Ig

Synonyms

G14 Gastrin 6, G17 Gastrin 14, G34 Gastrin, G52 Big gastrin, G6, GAS, GAST, gastrin, Gastrin 17, Gastrin 34, Gastrin component I Gastrin 52, Gastrin component II, Gastrin component III

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Validation Data Gallery

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  IHC staining of human stomach using 60346-1-Ig

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 60346-1-Ig (Gastrin antibody) at dilution of 1:350 (under 10x lens).

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  IHC staining of human stomach using 60346-1-Ig

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 60346-1-Ig (Gastrin antibody) at dilution of 1:350 (under 40x lens).

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Tested Applications

• Positive IHC detected in: human stomach tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:100-1:500

Sample-dependent, check data in validation data gallery

Published Applications

• IF: See 1 publications below

Product Information

60346-1-Ig targets Gastrin in IHC, IF,ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: Gastrin fusion protein Ag12795
• Full Name: gastrin
• Calculated molecular weight: 101 aa, 11 kDa
• GenBank accession number: BC069724
• Gene symbol: GAST
• Gene ID (NCBI): 2520
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Gastrin is a hormone produced primarily by G-cells in the stomach, where it functions to stimulate acid secretion by gastric parietal cells. Gastrin is a promiscuous hormone. Thus, the gastrin gene is expressed in common cancers such as bronchogenic, colorectal, ovarian and pancreatic carcinomas.

Publications

Species	Application	Title
human	IF	Cell; High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells.; Authors - Joep Beumer