Published Applications
| WB | See 1 publications below |
Product Information
15322-1-AP targets HDAC7 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HDAC7 fusion protein Ag1101 Predict reactive species |
| Full Name | histone deacetylase 7 |
| Calculated Molecular Weight | 103 kDa |
| GenBank Accession Number | BC006453 |
| Gene Symbol | HDAC7 |
| Gene ID (NCBI) | 51564 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WUI4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Histone deacetylases (HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin. At least 4 classes of HDAC were identified. Just like other class II HDACs, HDAC7 shuttles in and out of the nucleus depending on different signals. This gene encoding human HDAC7 is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human HDAC7.
Publications
| Species | Application | Title |
|---|---|---|
J Cell Mol Med HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury. |
