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HOPX Polyclonal antibody

HOPX Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 11419-1-AP


CAMEO, HOD, Homeodomain only protein, HOP, HOP homeobox, HOPX, LAGY, NECC1, OB1, Odd homeobox protein 1, SMAP31, TOTO

Tested Applications

Positive WB detected inmouse lung tissue, mouse small intestine tissue, rat lung tissue

Recommended dilution

Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11419-1-AP targets HOPX in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HOPX fusion protein Ag1979
Full Name HOP homeobox
Calculated Molecular Weight 73 aa, 8 kDa
Observed Molecular Weight 8-12 kDa
GenBank Accession NumberBC014225
Gene Symbol HOPX
Gene ID (NCBI) 84525
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

HOPX (Homeodomain-only protein) gene has various synonyms including HOD, HOP, OB1, LAGY and NECC1. The protein encoded by this gene is an unusual homeodomain protein that lacks certain conserved residues required for DNA binding. HOPX has diverse effects on cardiac growth. Manipulation of Hopx function in murine models is associated with cardiac hypertrophy, dilation and fibrosis. HOPX protein acts as an antagonist to the serum response factor (SRF), which regulates the opposing processes of cell proliferation and differentiation. Overexpression of HOPX causes cardiac hypertrophy. HOPX protein can inhibit SRF-dependent transcriptional activation by recruiting histone deacetylase (HDAC) activity.


Product Specific Protocols
WB protocol for HOPX antibody 11419-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




Cell stress in cortical organoids impairs molecular subtype specification.

Authors - Aparna Bhaduri


Origins and Proliferative States of Human Oligodendrocyte Precursor Cells.

Authors - Wei Huang

Cancer Cell

Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma.

Authors - Lindsay M LaFave

Cancer Cell

Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis.

Authors - William K C Cheung

Cell Stem Cell

LIF signaling regulates outer radial glial to interneuron fate during human cortical development

Authors - Madeline G Andrews

Protein Cell

BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period

Authors - Zhenmeiyu Li


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Ana (Verified Customer) (11-10-2020)

We recently published with this paper: PubMed ID: 32819430 Images are within the manuscript.Protocol information: We used Citirc Acid Buffer Antigen Retrieval

  • Applications: Immunohistochemistry
  • Primary Antibody Dilution: 1:250
  • Cell Tissue Type: Human Brain (fetal), Paraffin Processed
HOPX Antibody Immunohistochemistry validation (1:250 dilution) in Human Brain (fetal), Paraffin Processed (Cat no:11419-1-AP)

Nicole (Verified Customer) (07-23-2019)

Used to mark stem cell cultures for differentiation into neural like cells

  • Applications: Immunohistochemistry, Immunofluorescence,
  • Cell Tissue Type: Stem Cell culture