Recombinant Human BTN3A3 protein (rFc Tag)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg4892

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Validation Data Gallery

• 

  Purity of Recombinant Human BTN3A3 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

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Product Information

• Purity: >90 %, SDS-PAGE
• Endotoxin: <0.1 EU/μg protein, LAL method
• Activity:

  Not tested

• Expression: HEK293-derived Human BTN3A3 protein Gln30-Trp248 (Accession# O00478-1) with a rabbit IgG Fc tag at the N-terminus.
• GeneID: 10384
• Accession: O00478-1
• PredictedSize: 50.8 kDa
• SDS-PAGE: 50-60 kDa, reducing (R) conditions
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
• Reconstitution: Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
• Storage Conditions:
  It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

Butyrophilin Subfamily 3 Member A3 (BTN3A3) is a type I transmembrane protein belonging to the immunoglobulin (Ig) superfamily, which is expressed in many cancers. BTN3A3 might be involved in the regulation of cell proliferation by downregulating death-related genes. BTN3A3 may be a prognostic marker and a potential therapeutic target for ovarian cancer.

References:

1. Zhang Q, et al. (2023). J Invest Dermatol. 143(8):1439-1448.e21.
2. Chen S, et al. (2022). Front Oncol. 12:952425.