Speedy™ Human DOPA decarboxylase/DDC One-Step ELISA Kit
Cat no : SE50191
Synonyms
DDC, DOPA decarboxylase, AADC, Aromatic-L-amino-acid decarboxylase, EC:4.1.1.28
Validation Data Gallery
Product Information
| Product name | Speedy™ Human DOPA decarboxylase/DDC One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma |
| Assay type | Sandwich |
| Sensitivity | 0.05 ng/mL |
| Range | 0.313-20 ng/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 1644 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human serum | 88% | 83%-92% |
IntraAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 9.89 | 0.91 | 9.20 |
| 2 | 8 | 2.39 | 0.11 | 4.60 |
| 3 | 8 | 1.21 | 0.04 | 3.31 |
InterAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 9.91 | 0.67 | 6.76 |
| 2 | 16 | 2.44 | 0.11 | 4.51 |
| 3 | 16 | 1.24 | 0.05 | 4.03 |
Background Information
DOPA decarboxylase (DDC), also known as aromatic l-amino acid decarboxylase, belongs to the pyridoxal-dependent aminotransferase superfamily. DDC is an enzyme that converts levodopa into dopamine, the latter being severely depleted in LBD due to the loss of dopaminergic neurons in the substantia nigra. DDC plays an important role in the dopaminergic system and participates in the uptake and decarboxylation of amine precursors in the peripheral tissues. It is reported that DDC may be a novel and potential marker for the detection of peritoneal micrometastases of gastric cancer.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | DDC, DOPA decarboxylase, AADC, Aromatic-L-amino-acid decarboxylase, EC:4.1.1.28 |