Speedy™ Human IL-18R1 One-Step ELISA Kit
Cat no : SE50239
Synonyms
IL18R1, CD218 antigen-like family member A, CD218a, EC:3.2.2.6, IL 18R 1
Validation Data Gallery
Product Information
| Product name | Speedy™ Human IL-18R1 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Cell lysate |
| Assay type | Sandwich |
| Sensitivity | 10.9 pg/mL |
| Range | 39-2500 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 8809 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Cell lysate | 90% | 86%-94% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 1,393.8 | 49.0 | 3.5 |
| 2 | 8 | 343.2 | 14.6 | 4.3 |
| 3 | 8 | 168.5 | 2.6 | 1.5 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 1,314.2 | 106.7 | 8.1 |
| 2 | 16 | 333.7 | 20.2 | 6.1 |
| 3 | 16 | 163.7 | 5.9 | 3.6 |
Background Information
IL-18R1 (CD218a) is a component of the interleukin-18 receptor (IL-18R) complex, which is critical for the signaling of IL-18, a pro-inflammatory cytokine. This receptor complex, consisting of IL-18R1 and the IL-18 receptor accessory protein (IL-18RAP), belongs to the immunoglobulin-like family of interleukin-1 receptors. IL-18R1 plays a significant role in inducing the production of interferon-gamma (IFN-γ) and other inflammatory cytokines, contributing to innate and adaptive immune responses. It is also suggested to play a role in hypertension and chronic kidney disease, where the IL-18/IL-18R1 signaling axis may have diagnostic and therapeutic potential.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | IL18R1, CD218 antigen-like family member A, CD218a, EC:3.2.2.6, IL 18R 1 |