Speedy™ Human L1CAM One-Step ELISA Kit
Cat no : SE50173
Synonyms
CAML1, CD171, HSAS, HSAS1, L1 cell adhesion molecule
Validation Data Gallery
Product Information
| Product name | Speedy™ Human L1CAM One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell lysate |
| Assay type | Sandwich |
| Sensitivity | 13.1 pg/mL |
| Range | 125-8000 pg/mL |
| Reactivity | Human |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 3897 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Human plasma | 97% | 92%-101% |
| Cell lysate | 93% | 90%-96% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 3,990.4 | 130.9 | 3.3 |
| 2 | 8 | 959.0 | 86.4 | 9.0 |
| 3 | 8 | 496.8 | 38.9 | 7.8 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 3,984.7 | 249.4 | 6.3 |
| 2 | 16 | 950.4 | 71.2 | 7.5 |
| 3 | 16 | 489.4 | 29.4 | 6.0 |
Background Information
L1CAM, also known as NCAM-L1 or CD171, is a cell adhesion molecule of the immunoglobulin superfamily. It is a 200-220 kDa transmembrane glycoprotein composed of six Ig-like domains and five fibronectin type III repeats followed by a transmembrane region and a highly conserved cytoplasmic tail. L1CAM is primarily expressed in the nervous system and is involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, cerebellar granule cell migration, neurite outgrowth on Schwann cells and interactions among epithelial cells of intestinal crypts. L1CAM is overexpressed in many human cancers and is often associated with bad prognosis.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | CAML1, CD171, HSAS, HSAS1, L1 cell adhesion molecule |