Recombinant Human TDGF1 protein (mFc Tag)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

mFc Tag

Activity

not tested

Cat no : Eg3922

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Validation Data Gallery

• 

  Purity of Recombinant Human TDGF1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

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Product Information

• Purity: >90 %, SDS-PAGE
• Endotoxin: <0.1 EU/μg protein, LAL method
• Activity:

  Not tested

• Expression: HEK293-derived Human TDGF1 protein Leu31-Thr172 (Accession# P13385) with a mosue IgG Fc tag at the C-terminus.
• GeneID: 6997
• Accession: P13385
• PredictedSize: 42.6 kDa
• SDS-PAGE: 45-57 kDa, reducing (R) conditions
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
• Reconstitution: Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
• Storage Conditions:
  It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

Transforming Growth Factor-beta 1 (TGF-β1) is a multifunctional protein that plays a crucial role in various biological processes. It is a member of the TGF-β superfamily, which includes TGF-β1, TGF-β2, and TGF-β3. These proteins are structurally related and have diverse functions in cell biology. TGF-β1 is particularly important in regulating cell proliferation, differentiation, apoptosis, and immune responses. It is also involved in the development of various diseases, including cancer, fibrosis, and autoimmune disorders.

References:

1.	Miyoshi N, et al. (2010) Int J Oncol. 36(3):563-8. 
2.	Barnes RM, et al.  (2016) Development. 143(5):774-9. 
3.	Liguori G, et al. (1997) Mamm Genome. 8(7):502-5. 
4.	Behrens AN, et al. (2012) J Clin Exp Cardiolog. 11:1-4.