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Recombinant Human CD268/BAFFR protein (rFc Tag)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg1922

Validation Data Gallery

  • Purity of Recombinant Human CD268 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CD268 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

Product Information

Purity >90 %, SDS-PAGE
Endotoxin <0.1 EU/μg protein, LAL method
Activity 
Not tested
Expression HEK293-derived Human CD268 protein Ser7-Ala71 (Accession# Q96RJ3-1) with a rabbit IgG Fc tag at the C-terminus.
GeneID 115650
Accession Q96RJ3-1
PredictedSize 32.8 kDa
SDS-PAGE 37-52 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

TNFRSF13C (Tumor necrosis factor receptor superfamily member 13C), also known as BAFF-R, BR3, is a widely expressed receptor of important functional relevance for T and B cell responses, represents an attractive target for intervention in autoimmune diseases. The absolute absence of BAFF-R on earlier precursors suggests that a complete BCR positively regulates BAFF-R expression. BAFF/BAFF-R signaling axis in the pathogenesis of autoimmune human diseases and B lineage malignancies have largely prompted studies focusing on BAFF expression.

References:

1. Ye Q, et al. (2004). Eur J Immunol. Oct;34(10):2750-2759.
2. Ng LG, et al. (2004). J Immunol. Jul 15;173(2):807-817. 
3. Mihalcik S.A., et al. (2010). J Immunol. Jul 15;185(2):1045-54.