IBTK Polyclonal antibody, PBS Only

• 

  WB analysis using 31462-1-AP (same clone as 31462-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31462-1-AP (IBTK antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31462-1-PBS in a different storage buffer formulation.

IBTK Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31462-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

RP1 93K22.1, KIAA1417, BTKI, BTBD26

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Product Information

31462-1-PBS targets IBTK in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag35421

  Product name: Recombinant human IBTK protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 850-1000 aa of BC143745

  Sequence: VADQLLITRLKEICEVALTEKLTLKNAAMLLEFAAMYSAKQLKLSCLQFIGLNMAALLEARSLDVLSDGVLKDLSEFYRKMIPAMDRRVITPYQDGPDISYLEVEDGDIFLKEEINMEQNHSETMFKKAKTKAKKKPRKRSDSSGGYNLSD

• Full Name: inhibitor of Bruton agammaglobulinemia tyrosine kinase
• Observed Molecular Weight: 140-160kDa
• GenBank Accession Number: BC143745
• Gene Symbol: IBTK
• Gene ID (NCBI): 25998
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q9P2D0
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

IBTK, also known as BTKI and KIAA1417, which is involved in stress response and tumor growth. It has 3 isoforms and has been found to be hyper-expressed in chronic lymphocytic leukemia and correlated with disease progression (PMID: 29317636).