Product Information
22203-1-AP targets IRE1/ERN1 in WB, IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human, mouse, rat, bovine |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag17504 Product name: Recombinant human IRE1; ERN1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 121-500 aa of BC130405 Sequence: KQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDVKFDPGLKSKNKLNYLRNYWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSRDVEEKPAHAPARPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKELEKIQLLQQQQQQLPFHP Predict reactive species |
| Full Name | endoplasmic reticulum to nucleus signaling 1 |
| Calculated Molecular Weight | 977 aa, 110 kDa |
| GenBank Accession Number | BC130405 |
| Gene Symbol | IRE1 |
| Gene ID (NCBI) | 2081 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O75460 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Publications
What published studies show
The IRE1/ERN1 Polyclonal antibody (Cat# 22203-1-AP) has 7 citations published in Free Radical Biology and Medicine, ACS Applied Materials & Interfaces, World Journal of Gastroenterology, Toxics, Environmental Toxicology, Food and Chemical Toxicology, and Toxicology and Industrial Health. The research fields span endoplasmic reticulum stress, apoptosis, ferroptosis, liver injury, kidney injury, wound healing, and cell cycle regulation across human, mouse, rat, and bovine models.
| Species | Application | Title |
|---|---|---|
Free Radic Biol Med UFL1 regulates cellular homeostasis by targeting endoplasmic reticulum and mitochondria in NEFA-stimulated bovine mammary epithelial cells via the IRE1α/XBP1 pathway | ||
ACS Appl Mater Interfaces Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds with Endoplasmic Reticulum Stress-Relieving Properties for Promoted Scarless Wound Healing | ||
World J Gastroenterol Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress | ||
Toxics Cadmium-Induced Kidney Apoptosis Based on the IRE1α-XBP1 Signaling Pathway and the Protective Effect of Quercetin | ||
Environ Toxicol Naringin Induces ROS-Stimulated G1 Cell-Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma Cells | ||
Food Chem Toxicol Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice |
