CD11c/Integrin alpha X Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60258-1-Ig |CloneNo.: 2F1C10

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Con: 300 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human spleen tissue, HL-60 cells, THP-1 cells, U-937 cells

Positive IHC detected in:
human tonsillitis tissue, human breast cancer tissue, human lung cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:100-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
integrin, alpha X (complement component 3 receptor 4 subunit)

Calculated molecular weight:
1169aa,129 kDa

Observed molecular weight:
145 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ITGAX

Synonyms
CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6
Background

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a 145-150 kDa type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.


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