LINGO1 Polyclonal antibody, PBS Only

• 

  WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat brain using 19097-1-AP (same clone as 19097-1-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

LINGO1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 19097-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

19097-1-PBS targets LINGO1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag13553

  Product name: Recombinant human LINGO1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 36-351 aa of BC011057

  Sequence: SGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLE

• Full Name: leucine rich repeat and Ig domain containing 1
• Calculated Molecular Weight: 70 kDa
• Observed Molecular Weight: 83 kDa
• GenBank Accession Number: BC011057
• Gene Symbol: LINGO1
• Gene ID (NCBI): 84894
• RRID: AB_10638484
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q96FE5
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

LINGO-1 is a transmembrane receptor that contains 12 leucine-rich repeats and an immunoglobulin domain. It is expressed primarily in the central nervous system. LINGO-1 binds Nogo-66 receptor (NgR) and p75 and that is a functional component of the NgR/p75 signaling complex (PMID: 14966521). This protein has a calculated molecular weight of 70 kDa and migrates at higher molecular weight due to glycosylation (PMID: 21872576; 25257685; 18326721).