LPL Polyclonal antibody

LPL Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 16899-1-AP

Synonyms

HDLCQ11, LIPD, lipoprotein lipase, LPL



Tested Applications

Positive WB detected inMCF-7 cells, HeLa cells, mouse skeletal muscle tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 1 publications below

Product Information

The immunogen of 16899-1-AP is LPL Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LPL fusion protein Ag10431
Full Name lipoprotein lipase
Calculated molecular weight 475 aa, 53 kDa
Observed molecular weight 53 kDa
GenBank accession numberBC011353
Gene symbol LPL
Gene ID (NCBI) 4023
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

LPL(lipoprotein lipase) is also named as LIPD and belongs to the AB hydrolase superfamily. LPL catalyses the hydrolysis of the triacylglycerol component of circulating chylomicrons and very low density lipoproteins. It plays a role in the binding of lipoprotein particles to cell-surface molecules, including sulfated glycosaminoglycans (GAGs)(PMID:21177248). The gene encodes a protein of 475 amino acids that becomes a mature protein of 448 residues after cleavage of a signal peptide. This protein is highly glycosylated and functions as a head-to-tail dimer under well-defined conditions(PMID:11154699).

Publications

SpeciesApplicationTitle

Diabetes

Tissue-specific splicing and dietary interaction of a mutant As160 allele determine muscle metabolic fitness in rodents.

Authors - Xinyu Yang
mouseWB

Diabetes

Rab8a Deficiency in Skeletal Muscle Causes Hyperlipidemia and Hepatosteatosis Via Impairment of Muscle Lipid Uptake and Storage.

Authors - Qiaoli Chen