MAGEC2 Polyclonal antibody

MAGEC2 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 10280-1-AP

Synonyms

Cancer/testis antigen 10, CT10, HCA587, MAGE C2 antigen, MAGE E1 antigen, MAGEC2, MAGEE1, melanoma antigen family C, 2, Melanoma associated antigen C2



Tested Applications

Positive IHC detected inhuman testis tissue, human breast cancer tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Published Applications

IHCSee 2 publications below

Product Information

10280-1-AP targets MAGEC2 in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen MAGEC2 fusion protein Ag0418
Full Name melanoma antigen family C, 2
Calculated molecular weight 373 aa, 41 kDa
GenBank accession numberBC005891
Gene symbol MAGEC2
Gene ID (NCBI) 51438
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Melanoma antigen family C, 2(MAGEC2, synonyms: CT10, HCA587, MAGEE1, MGC13377) is related to members of the MAGEC gene family. MAGEC2 is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and other MAGEC genes are clustered on chromosome Xq26-q27.

Protocols

Product Specific Protocols
WB protocol for MAGEC2 antibody 10280-1-APDownload protocol
IHC protocol for MAGEC2 antibody 10280-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

Laryngoscope Investig Otolaryngol

The expression of the cancer testis antigen MAGE A4: A favorable prognostic biomarker in salivary gland carcinomas related to low tumor grading.

Authors - Domenic Vital
humanIHC

Hum Pathol

Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers.

Authors - Annikka Weissferdt
humanIHC

PLoS One

γ-Radiation promotes immunological recognition of cancer cells through increased expression of cancer-testis antigens in vitro and in vivo.

Authors - Sharma Anu A