MAGOH Polyclonal antibody

MAGOH Polyclonal Antibody for IHC, IP, WB, ELISA

Host / Isotype

Rabbit / IgG


human and More (1)





Cat no : 12347-1-AP


MAGOH, MAGOHA, Protein mago nashi homolog

Tested Applications

Positive WB detected inK-562 cells, HeLa cells, HL-60 cells, human brain tissue, Raji cells
Positive IP detected inK-562 cells
Positive IHC detected inhuman ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

12347-1-AP targets MAGOH in WB, IP, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen MAGOH fusion protein Ag3004
Full Name mago-nashi homolog, proliferation-associated (Drosophila)
Calculated molecular weight 146 aa, 17 kDa
Observed molecular weight 17 kDa
GenBank accession numberBC018211
Gene symbol MAGOH
Gene ID (NCBI) 4116
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

MAGOH, belonging to the mago nashi family, is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). MAGOH regulates the transcriptional activation of STAT3 by interfering complex formation between STAT3 and a core EJC component Y14.


Product Specific Protocols
WB protocol for MAGOH antibody 12347-1-APDownload protocol
IHC protocol for MAGOH antibody 12347-1-APDownload protocol
IP protocol for MAGOH antibody 12347-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cell Rep

Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.

Authors - Duygu Kuzuoglu-Ozturk
  • KO Validated

J Exp Zool B Mol Dev Evol

Mago, a vertebrate homolog of Drosophila Mago nashi protein, is a component of the chromatoid body in the cytoplasm of the postmeiotic spermatid.

Authors - Zhao Wei W


Generation of a Magoh conditional allele in mice.

Authors - John J McMahon


Dosage-dependent requirements of Magoh for cortical interneuron generation and survival.

Authors - Charles J Sheehan

PLoS Genet

Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.

Authors - Hanqian Mao

Nat Neurosci

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

Authors - Silver Debra L DL