MMACHC Monoclonal antibody, PBS Only

MMACHC Monoclonal Antibody for WB, IF/ICC, FC (Intra), ELISA
Cat No. 66609-1-PBS
Clone No.4G10A11

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, IF/ICC, FC (Intra), ELISA

4G10A11, Alkylcobalamin:glutathione S-alkyltransferase, CblC, cyanide-eliminating, Cyanocobalamin reductase

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

66609-1-PBS targets MMACHC in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen MMACHC fusion protein Ag15001 Predict reactive species
Full Name methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
Calculated Molecular Weight 282 aa, 32 kDa
Observed Molecular Weight 32 kDa
GenBank Accession NumberBC006122
Gene Symbol MMACHC
Gene ID (NCBI) 25974
RRIDAB_2881969
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9Y4U1
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

MMACHC, also named as CblC, is located on chromosome 1 and comprises four coding exons. Human MMACHC catalyzes the reductive decyanation of cyanocobalamin and may serve as a trafficking chaperone for intracellular cobalamin. It also catalyzes the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin. NMACHC binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives.

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