MSH6 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66172-1-Ig |CloneNo.: 2E10B2

Featured Product KD/KO validated

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Freight/Packing

Con: 154 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HEK-293 cells, HEK-293

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human colon cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mutS homolog 6 (E. coli)

Calculated molecular weight:
153 kDa

Observed molecular weight:
160 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MSH6

Synonyms
G/T mismatch binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, MSH6, MutS alpha 160 kDa subunit, mutS homolog 6 (E. coli), p160
Background

MSH6, also named as DNA mismatch repair protein Msh6 or GTMBP, is a 1360 amino acid protein, which contains one PWWP domain and belongs to the DNA mismatch repair MutS family. MSH6 localizes in the nucleus and is a component of the post-replicative DNA mismatch repair system. Msh2 and Msh6 form a protein complex required to repair mismatches generated during DNA replication.


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