MUC16,CA125 Monoclonal antibody
MUC16,CA125 Monoclonal Antibody for IHC,ELISA
Host / Isotype
Mouse / IgG1
Cat no : 60261-1-Ig
|Positive IHC detected in||human ovary tumor tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
60261-1-Ig targets MUC16,CA125 in IHC,ELISA applications and shows reactivity with human samples.
|Host / Isotype||Mouse / IgG1|
|Full Name||mucin 16, cell surface associated|
|Calculated molecular weight||1519 kDa|
|GenBank accession number||NM_024690|
|Gene ID (NCBI)||94025|
|Purification Method||Protein G purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.
|Product Specific Protocols|
|IHC protocol for MUC16,CA125 antibody 60261-1-Ig||Download protocol|
|Click here to view our Standard Protocols|
Int J Oncol
Lewis antigen‑negative pancreatic cancer: An aggressive subgroup.
MUC16 C terminal-induced secretion of tumor-derived IL-6 contributes to tumor-associated Treg enrichment in pancreatic cancer.