Speedy™ Mouse CSF1R/CD115 One-Step ELISA Kit
Cat no : SE60071
Synonyms
Csf1r, CD115, CSF 1R, CSF-1 receptor, Csfmr
Validation Data Gallery
Product Information
| Product name | Speedy™ Mouse CSF1R/CD115 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma, Cell culture supernatant, Cell lysate, Tissue lysate |
| Assay type | Sandwich |
| Sensitivity | 1.8 pg/mL |
| Range | 125-8000 pg/mL |
| Reactivity | Mouse |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 12978 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Mouse serum | 97% | 90%-102% |
| Cell culture supernatant | 93% | 89%-98% |
| Cell lysate | 87% | 83%-91% |
IntraAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 3,750.9 | 99.7 | 2.7 |
| 2 | 8 | 952.0 | 13.6 | 1.4 |
| 3 | 8 | 489.6 | 10.2 | 2.1 |
InterAssay
| Sample | n | mean ( pg/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 3,716.4 | 99.7 | 2.7 |
| 2 | 16 | 927.9 | 27.4 | 3.0 |
| 3 | 16 | 475.5 | 16.4 | 3.4 |
Background Information
The CSF-1 receptor (CSF1R), also called CD115, is activated by the homodimeric growth factors colony-stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in development and in innate immunity by regulating the development of most tissue macrophages and osteoclasts, of Langerhans cells of the skin, of Paneth cells of the small intestine, and of brain microglia. It also regulates the differentiation of neural progenitor cells and controls the functions of oocytes and trophoblastic cells in the female reproductive tract. Owing to this broad tissue expression pattern, it plays a central role in neoplastic, inflammatory, and neurological diseases.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | Csf1r, CD115, CSF 1R, CSF-1 receptor, Csfmr |