Speedy™ Mouse/Rat IGFBP2 One-Step ELISA Kit
Cat no : SE60032
Synonyms
IBP-2, IGF-binding protein 2, IGFBP-2, Insulin-like growth factor-binding protein 2, mIGFBP-2
Validation Data Gallery
Product Information
| Product name | Speedy™ Mouse/Rat IGFBP2 One-Step ELISA Kit |
| Tests | 1 X 96 well plate |
| Sample type | Mouse serum, Mouse plasma, Rat serum, Rat plasma |
| Assay type | Sandwich |
| Sensitivity | 0.05 ng/mL |
| Range | 0.313-20 ng/mL |
| Reactivity | Mouse/Rat |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 16008 |
Recovery
| Sample Type | Average | Range |
|---|---|---|
| Mouse serum | 115% | 110%-119% |
| Rat serum | 117% | 112%-120% |
IntraAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 8 | 11.14 | 0.29 | 2.60 |
| 2 | 8 | 2.74 | 0.05 | 1.82 |
| 3 | 8 | 1.40 | 0.05 | 3.57 |
InterAssay
| Sample | n | mean ( ng/mL) | SD | CV% |
|---|---|---|---|---|
| 1 | 16 | 11.12 | 0.24 | 2.16 |
| 2 | 16 | 2.71 | 0.09 | 3.32 |
| 3 | 16 | 1.38 | 0.07 | 5.07 |
Background Information
IGFBP2 (insulin-like growth factor-binding protein 2) is a secreted protein belonging to the IGF-binding protein family, which is widely involved in a variety of biological processes such as cell growth, differentiation, apoptosis and tumor progression. It regulates the activity of the IGF signaling pathway by binding to IGF-I and IGF-II, prolongs the half-life of IGF, and affects its bioavailability. IGFBP2 exhibits aberrant expression in a wide range of diseases, especially in tumors, where its high expression is closely related to malignant progression of tumors, metastasis and poor prognosis. In addition, IGFBP2 plays important roles in physiological processes such as nerve repair, energy metabolism and cell proliferation. For example, it promotes neuronal regeneration and glial cell proliferation, improves insulin resistance, and regulates the cell cycle. In the field of oncology, IGFBP2 can be used as both potential diagnostic marker and therapeutic target.
Properties
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| Synonyms | IBP-2, IGF-binding protein 2, IGFBP-2, Insulin-like growth factor-binding protein 2, mIGFBP-2 |