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MultiProTM 5CFLX Anti-Human CD11a (TS2/4)

CD11a Monoclonal Antibody for

Host / Isotype

Mouse / IgG1, kappa

Reactivity

Human

Applications

Conjugate

5CFLX

CloneNo.

TS2/4

Cat no : G65194-1-5C

Synonyms

CD11A, Integrin alpha L, ITGAL, LFA 1, LFA 1A, LFA1A

Validation Data Gallery

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  • Single Cell Sequencing experiment G65194-1-5C on Resting PBMC

    Single Cell Sequencing experiment G65194-1-5C on Resting PBMC

    G65194-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G65194-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G65194-1-5C on PBMC treated with 4hr LPS + TI

    G65194-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G65194-1-5C on Resting PBMC

    Single Cell Sequencing experiment G65194-1-5C on Resting PBMC

    G65194-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

Tested Applications

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
Positive Single Cell detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.

Recommended dilution

ApplicationDilution
SINGLE CELL (INTRA)<0.5ug/test
SINGLE CELL<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

G65194-1-5C targets CD11a in applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1, kappa
Class Oligo Conjugate
Type Monoclonal
Immunogen HLA-DR CTL line
Full Name MultiProTM 5CFLX Anti-Human CD11a (TS2/4)
Calculated Molecular Weight 129 kDa
GenBank Accession NumberBC008777
Gene Symbol ITGAL
Gene ID (NCBI) 3683
Conjugate 5CFLX
Form Liquid
Storage Buffer PBS with 1mM EDTA and 0.09% sodium azide
Storage Conditions2-8°C

Background Information

CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).

Protocols

MultiPro™ Cell Surface and Intracellular Staining ProtocolDownload protocol
10x Genomics Cell Surface Protein Only Staining ProtocolDownload protocol