CFAP45 Polyclonal antibody, PBS Only

• 

  WB analysis using 21077-1-AP (same clone as 21077-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21077-1-AP (NESG1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21077-1-PBS in a different storage buffer formulation.

• 

  WB analysis of rat testis using 21077-1-AP (same clone as 21077-1-PBS)

  rat testis tissue were subjected to SDS PAGE followed by western blot with 21077-1-AP (NESG1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21077-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse testis using 21077-1-AP (same clone as 21077-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 21077-1-AP (NESG1 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21077-1-PBS in a different storage buffer formulation.

CFAP45 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 21077-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

CCDC19

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Product Information

21077-1-PBS targets CFAP45 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag15257

  Product name: Recombinant human NESG1 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 202-551 aa of BC027874

  Sequence: KCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEELRATGLPEKYCIEAERKANILPATSVN

• Full Name: coiled-coil domain containing 19
• Calculated Molecular Weight: 551 aa, 66 kDa
• Observed Molecular Weight: 66 kDa
• GenBank Accession Number: BC027874
• Gene Symbol: CCDC19
• Gene ID (NCBI): 25790
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9UL16
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CCDC19, also named as NESG1, CFAP45, is specifically expressed in human nasopharynx and trachea, and decreased or absent in nasopharyngeal carcinoma (NPC) tissues and cell lines. In addition, the levels of NESG1 protein are significantly greater in the low-grade NPC tissues than that in the high-grade NPC tissues. NESG1 also significantly regulats the expression of cell cycle regulators CCNA1 and p21. NESG1 may act as a tumor suppressor by inhibiting cell proliferation, invasion and migration of NPC cells.