BNP Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13299-1-AP

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Con: 46 μg/150 μl

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Species specificity:
human

Positive IHC detected in:
human brain tissue, human brain tissue, human heart tissue

Recommended dilution:
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
natriuretic peptide precursor B

Calculated molecular weight:
134aa,15 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NPPB

Synonyms
BNP, BNP(1 32), Natriuretic peptides B, NPPB
Background

NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.


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