PAX4 Monoclonal antibody
PAX4 Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
CloneNo.
1B2C6
Cat no : 66064-1-Ig
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
The immunogen of 66064-1-Ig is PAX4 Fusion Protein expressed in E. coli.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | PAX4 fusion protein Ag17007 |
Full Name | paired box 4 |
Calculated Molecular Weight | 343 aa, 37 kDa |
GenBank Accession Number | BC074761 |
Gene Symbol | PAX4 |
Gene ID (NCBI) | 5078 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
PAX4, a paired-box transcription factor, is a key regulator of pancreatic islet cell growth and differentiation. Differentiation of endoderm-derived endocrine pancreas is mediated through PAX4 and PAX6. PAX4 may act as a PAX6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. PAX4 has the potential to function as a tumor suppressor in human melanoma.