Product Information
13146-1-PBS targets POP5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag3710 Product name: Recombinant human POP5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-163 aa of BC012505 Sequence: MVRFKHRYLLCELVSDDPRCRLSLDDRVLSSLVRDTIARVHGTFGAAACSIGFAVRYLNAYTGIVLLRCRKEFYQLVWSALPFITYLENKGHRYPCFFNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTRSCLLEEEEESGEEAAEAME Predict reactive species |
| Full Name | processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) |
| Calculated Molecular Weight | 163 aa, 19 kDa |
| Observed Molecular Weight | 19 kDa |
| GenBank Accession Number | BC012505 |
| Gene Symbol | POP5 |
| Gene ID (NCBI) | 51367 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q969H6 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
POP5 is a component of ribonuclease P and MRP ribonuclease complex that cleaves pre-rRNA sequences and generates mature tRNA molecules. Endogenous hPop5 protein is localized in the nucleus and accumulates in the nucleolus, which is consistent with its association with RNase MRP and RNase P. The human Pop5 cDNA encodes a protein of 163 amino acids with a predicted molecular mass of 18.8 kDa (PMID: 11413139).

