PRDM2 Polyclonal antibody

PRDM2 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 27718-1-AP

Synonyms

GATA 3 binding protein G3B, HUMHOXY1, KMT8, Lysine N methyltransferase 8, MTB ZF, MTE binding protein, PR domain containing protein 2, PRDM2, RIZ, RIZ1, RIZ2, Zinc finger protein RIZ



Tested Applications

Positive WB detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Sample-dependent, check data in validation data gallery

Product Information

27718-1-AP targets PRDM2 in WB,ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PRDM2 fusion protein Ag26769
Full Name PR domain containing 2, with ZNF domain
Calculated molecular weight 189 kDa
Observed molecular weight 250-280 kDa
GenBank accession numberNM_001007257
Gene symbol PRDM2
Gene ID (NCBI) 7799
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

PRDM2, also named as KMT8, RIZ, is a 1718 amino acid protein, which belongs to the class V-like SAM-binding methyltransferase superfamily. PRDM2 localizes in the nucleus and is highly expressed in retinoblastoma cell lines and in brain tumors and is also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. PRDM2 as a S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. The calculated molecular weight of PRDM2 is about 189 kDa. PRDM2 exists some isoforms with 250 kDa and 280 kDa. (PMID: 26040698)

Protocols

Product Specific Protocols
WB protocol for PRDM2 antibody 27718-1-APDownload protocol
Standard Protocols
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