PRPS2 Recombinant antibody, PBS Only

• 

  WB analysis using 85090-5-RR (same clone as 85090-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85090-5-RR (PRPS2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85090-5-PBS in a different storage buffer formulation.

• 

  WB analysis of rat spleen using 85090-5-RR (same clone as 85090-5-PBS)

  rat spleen tissue were subjected to SDS PAGE followed by western blot with 85090-5-RR (PRPS2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85090-5-PBS in a different storage buffer formulation.

PRPS2 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85090-5-PBS

Clone No.242657G2

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

242657G2, EC:2.7.6.1, PPRibP, PRS II, PRSII

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Product Information

85090-5-PBS targets PRPS2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: PRPS2 fusion protein Ag25785
• Full Name: phosphoribosyl pyrophosphate synthetase 2
• Observed Molecular Weight: 30-34 kDa
• GenBank Accession Number: BC119662
• Gene Symbol: PRPS2
• Gene ID (NCBI): 5634
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P11908
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

PRPS (phosphoribosyl pyrophosphate synthetase) proteins catalyze the synthesis of phosphoribosyl pyrophosphate (PRPP). Three human PRPS isoforms exist and are encoded by three different genes. PRPS1 and PRPS2 (also known as PRS1 and PRS2, respectively) are ubiquitously expressed, while PRPS3 (also known as PRPS1L1) is specific to the testis. PRPP is an important substrate synthesized from MgATP and ribose-5-phosphate in a reaction that requires inorganic phosphate and magnesium as a cofactor. PRPP is essential in the synthesis of nearly all nucleotides, implying that PRPS proteins play an important role in nucleotide biosynthesis and purine metabolism. PRPS2 is a 318 amino acid protein that exists as a homodimer and a hexamer composed of three homodimers.