Paxillin Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10029-1-Ig

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Freight/Packing

Con: 180 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse brain tissue, COLO 320 cells, Jurkat cells, MCF-7 cells

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human liver cancer tissue

Positive IF detected in:
HepG2 cells,NIH/3T3 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Protein A purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Recombinant Protein

Full name:
paxillin

Calculated molecular weight:
68 kDa

Observed molecular weight:
68 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PXN

Synonyms
FLJ16691, paxillin, PXN
Background

PXN (paxillin) is a 68 kDa scaffold protein that interacts with multiple structural and signaling proteins and regulates cell adhesion, migration, proliferation, and apoptosis. PXN is thought to play an important role in tumor migration, invasion, and metastasis (21045234). PXN has been identified as a direct substrate of protein tyrosine phosphatase receptor-type T (PTPRT), a potent tumor suppressor gene. Increased phospho-PXN at tyrosine residue 88 (Y88) has been found as a common feature of human colon cancers (20133777).


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