RASGRF2-Specific Polyclonal antibody
RASGRF2-Specific Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
Cat no : 19717-1-AP
Synonyms
Validation Data Gallery
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
19717-1-AP targets RASGRF2-Specific in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide |
| Full Name | Ras protein-specific guanine nucleotide-releasing factor 2 |
| Calculated Molecular Weight | 141 kDa |
| GenBank Accession Number | NM_006909 |
| Gene Symbol | RASGRF2 |
| Gene ID (NCBI) | 5924 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
RASGRF2, also named as GRF2, fnctions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. RASGRF2 preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. RASGRF2 functions in synaptic plasticity by contributing to the induction of long term potentiation. This antibody is specific to RASGRF2.
Publications
| Species | Application | Title |
|---|---|---|
Mol Biol Cell Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation. |
