|Positive WB detected in||pig retina tissue, rat retina tissue|
|Western Blot (WB)||WB : 1:2500-1:10000|
|Sample-dependent, check data in validation data gallery|
66521-1-Ig targets Recoverin in WB, ELISA applications and shows reactivity with Human, rat, pig, mouse samples.
|Tested Reactivity||Human, rat, pig, mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recoverin fusion protein Ag0119|
|Calculated molecular weight||24 kDa|
|Observed molecular weight||23 kDa|
|GenBank accession number||BC001720|
|Gene ID (NCBI)||5957|
|Purification Method||Protein G purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Recoverin, belonging to a family of the neuronal calcium sensor (NCS) proteins, has a restricted expression in retinal photoreceptors or neurons or neuroendocrine cells. It has been suggested to play a role in light and dark adaptation by regulating rhodopsin phosphorylation. Recently, it has been found that autoantibodies against recoverin (24 kDa) have been strongly associated with cancer -associated retinopathy (CAR) syndrome, a paraneoplastic disease of the retina. But functions of recoverin in cancer cells remain unknown.