SAP 97 Polyclonal antibody

SAP 97 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 55085-1-AP

Synonyms

Disks large homolog 1, DLG1, DLGH1, hdlg, SAP 97, SAP97, Synapse associated protein 97



Tested Applications

Positive WB detected inmouse lung tissue, HeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55085-1-AP targets SAP 97 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name discs, large homolog 1 (Drosophila)
Calculated Molecular Weight 100 kDa
Observed Molecular Weight 120 kDa, 130-140 kDa
GenBank Accession NumberNM_004087
Gene Symbol SAP97
Gene ID (NCBI) 1739
RRIDAB_11182375
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer 0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DLG1, also naemd as SAP97, hDlg and DLGH1, belongs to the MAGUK family. It is essential multidomain scaffolding protein required for normal development. DLG1 may play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. It regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. DLG1 is a functional regulator of Kv1.5 channel. The DLG1-MPP7 complex promotes epithelial cell polarity and tight junction formation. The antibody is specific to DLG1.

Protocols

Product Specific Protocols
WB protocol for SAP 97 antibody 55085-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse, humanIF

Kidney Int

Copy number variation analysis identifies novel CAKUT candidate genes in children with a solitary functioning kidney.

Authors - Rik Westland
ratWB

Neurochem Res

PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model

Authors - Jiawei Yang