SAPS2 Polyclonal antibody

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• KD/KO Validated

SAPS2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 26190-1-AP

Synonyms

KIAA0685, PP6R2, PPP6R2, SAP190, SAPS domain family member 2, SAPS domain family, member 2, SAPS2

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Validation Data Gallery

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  WB analysis using 26190-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 26190-1-AP (SAPS2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

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  WB analysis of HepG2 using 26190-1-AP

  WB result of SAPS2 antibody (26190-1-AP; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SAPS2 transfected HepG2 cells.

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Tested Applications

• Positive WB detected in: HeLa cells, HepG2 cells, Jurkat cells, MCF-7 cells

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:16000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

26190-1-AP targets SAPS2 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SAPS2 fusion protein Ag23458
• Full Name: SAPS domain family, member 2
• Calculated Molecular Weight: 105 kDa
• Observed Molecular Weight: 115-125 kDa
• GenBank Accession Number: BC000976
• Gene Symbol: SAPS2
• Gene ID (NCBI): 9701
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SAPS2 is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment.