SCN4B Polyclonal antibody, PBS Only

• 

  WB analysis of mouse heart using 55438-1-AP (same clone as 55438-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 55438-1-AP (SCN4B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55438-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 55438-1-AP (same clone as 55438-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55438-1-AP (SCN4B Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55438-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 55438-1-AP (same clone as 55438-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55438-1-AP (SCN4B Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 55438-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 55438-1-AP (same clone as 55438-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue slide using 55438-1-AP (SCN4B Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 55438-1-PBS in a different storage buffer formulation.

SCN4B Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 55438-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

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Product Information

55438-1-PBS targets SCN4B in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: sodium channel, voltage-gated, type IV, beta
• Calculated Molecular Weight: 25 kDa
• Observed Molecular Weight: 28 kDa
• GenBank Accession Number: NM_174934
• Gene Symbol: SCN4B
• Gene ID (NCBI): 6330
• RRID: AB_2881331
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8IWT1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Mammalian sodium channels are heterotrimers, composed of a central, pore-forming alpha subunit and two auxiliary beta subunits (PMID: 11486343). SCN4B (sodium channel subunit beta-4) is one of several sodium channel beta subunits, which modulate channel gating kinetics. SCN4B has an N-terminal signal peptide, a large extracellular domain predicted to form an Ig-like fold, a single transmembrane alpha helix, and a short cytoplasmic C terminus. Defects in SCN4B gene are a cause of long QT syndrome type 10 (LQT10).