SERPINA7 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 86893-4-RR (same clone as 86893-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86893-4-RR (SERPINA7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86893-4-PBS in a different storage buffer formulation.

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  IP experiment of HepG2 using 86893-4-RR (same clone as 86893-4-PBS)

  IP result of anti-SERPINA7 (IP:86893-4-RR, 4ug; Detection:86893-4-RR 1:600) with HepG2 cells lysate 1400 ug. This data was developed using the same antibody clone with 86893-4-PBS in a different storage buffer formulation.

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  Affinity of 86893-4-RR

  Biolayer interferometry (BLl) kinetic assays of 86893-4-RR against Human SERPINA7 were performed. The affinity constant is below 1 pM.

SERPINA7 Uni-rAb^® Recombinant Antibody for WB, IP, Indirect ELISA

Cat No. 86893-4-PBS

Clone No.251961H2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IP, Indirect ELISA

Synonyms

Serpin A7, SERPINA 7

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Product Information

86893-4-PBS targets SERPINA7 in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg3062

  Product name: recombinant human SERPINA7 protein

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 21-415 aa of NM_000354.5

  Sequence: ASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA

• Full Name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
• Calculated Molecular Weight: 46 kDa
• Observed Molecular Weight: 54 kDa
• GenBank Accession Number: NM_000354.5
• Gene Symbol: SERPINA7
• Gene ID (NCBI): 6906
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P05543
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

SERPINA7, also known as Thyroxine-binding globulin (TBG), is a 54 kDa acidic glycoprotein, consisting of a single polypeptide chain of 395 amino acids and four oligosaccharide chains. It is one of the major serum transport proteins of thyroid hormones (THs). Although high amounts of albumin are found in serum, TBG has a greater affinity for thyroxine (T4). Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG.