SFRS4 Polyclonal antibody
SFRS4 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IP, ELISA
Conjugate
Unconjugated
Cat no : 10152-2-AP
Synonyms
Validation Data Gallery
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
| IP | See 1 publications below |
Product Information
10152-2-AP targets SFRS4 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SFRS4 fusion protein Ag0204 |
| Full Name | splicing factor, arginine/serine-rich 4 |
| Calculated Molecular Weight | 57 kDa |
| GenBank Accession Number | BC002781 |
| Gene Symbol | SFRS4 |
| Gene ID (NCBI) | 6429 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Splicing factor, arginine/serine-rich 4 (SFRS4, synonym: SRP75). SR proteins are a family of proteins that have a common epitope that binds active sites of polymerase II transcription. SRp75 protein, like other SR proteins, contains an N-terminal RNA recognition motif (RRM), a glycine-rich region, an internal region homologous to the RRM, and a long (315-amino-acid) C-terminal domain composed predominantly of alternating serine and arginine residues. Four of the other SR family members have been shown to restore activity to an otherwise splicing-deficient extract. SRp75 together with SRp20 can also complement the splicing-deficient extract. The apparent molecular mass of dephosphorylated SRp75 is 57 kDa.
Publications
| Species | Application | Title |
|---|---|---|
J Virol Negative and positive mRNA splicing elements act competitively to regulate human immunodeficiency virus type 1 vif gene expression. | ||
PLoS One Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles. |
