Product Information
22815-1-PBS targets SLCO1B3/OATP1B3 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag18940 Product name: Recombinant human SLCO1B3 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 11-48 aa of BC105597 Sequence: AESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIM Predict reactive species |
| Full Name | solute carrier organic anion transporter family, member 1B3 |
| Calculated Molecular Weight | 702 aa, 77 kDa |
| Observed Molecular Weight | 70-75 kDa |
| GenBank Accession Number | BC105597 |
| Gene Symbol | SLCO1B3 |
| Gene ID (NCBI) | 28234 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NPD5 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).
