Tested Applications
| Positive WB detected in | L02 cells, MCF-7 cells, T-47D cells |
| Positive IP detected in | mouse testis tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
17567-1-AP targets ST7L in WB, IHC, IP, CoIP, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag11768 Product name: Recombinant human ST7L protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 234-575 aa of BC065501 Sequence: DCATAYVLLAEEEATTIVDAERLFKQALKAGETIYRQSQQCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYPDVQAVLAKYDDISLPKSAAICYTAALLKTRTVSEKFSPETASRRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHHVSVYPKKELPLFIHFTAGFCSSTAMIAILTHQFPEIMGIFAKAVLGLWCPQPWASSGFEENTQDLKSEDLGLSSG Predict reactive species |
| Full Name | suppression of tumorigenicity 7 like |
| Calculated Molecular Weight | 575 aa, 65 kDa |
| Observed Molecular Weight | 60-70 kDa |
| GenBank Accession Number | BC065501 |
| Gene Symbol | ST7L |
| Gene ID (NCBI) | 54879 |
| RRID | AB_2194882 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8TDW4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
ST7 (suppressor of tumorigenicity 7) gene has been proposed to be a tumor suppressor gene, product of which is a multi-pass membrane protein belonging to the ST7 family. ST7L (suppressor of tumorigenicity 7 protein-like) gene encodes a multi-pass membrane protein also belonging to the ST7 family, 8 isoforms produced by alternative splicing have been described . However, the molecular function of this gene product has not been determined so far.
Protocols
| Product Specific Protocols | |
|---|---|
| IP protocol for ST7L antibody 17567-1-AP | Download protocol |
| WB protocol for ST7L antibody 17567-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The ST7L Polyclonal antibody (Cat# 17567-1-AP) has 5 citations published in J Exp Clin Cancer Res, Advanced Science, Cell Death & Disease, International Journal of Molecular Medicine, and Life Sciences. The research fields span hepatocellular carcinoma, pancreatic cancer, cervical cancer, and severe sepsis, with applications including WB, CoIP, and IHC in human samples.
| Species | Application | Title |
|---|---|---|
J Exp Clin Cancer Res Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression. | ||
Adv Sci (Weinh) Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk. | ||
Cell Death Dis MicroRNA-23b functions as an oncogene and activates AKT/GSK3β/β-catenin signaling by targeting ST7L in hepatocellular carcinoma. | ||
Int J Mol Med miR-378 functions as an onco-miRNA by targeting the ST7L/Wnt/β-catenin pathway in cervical cancer. | ||
Life Sci Landscape of multiple tissues' gene expression pattern associated with severe sepsis: Genetic insights from Mendelian randomization and trans-omics analysis |
