STXBP1 Polyclonal antibody, PBS Only

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  WB analysis using 20562-1-AP (same clone as 20562-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20562-1-AP (STXBP1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 20562-1-AP (same clone as 20562-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 20562-1-AP (STXBP1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human brain using 20562-1-AP (same clone as 20562-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 20562-1-AP (STXBP1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 20562-1-AP (same clone as 20562-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using STXBP1 antibody (20562-1-AP) at dilution of 1:50 and CoraLite594-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

STXBP1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 20562-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

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Product Information

20562-1-PBS targets STXBP1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: syntaxin binding protein 1
• Calculated Molecular Weight: 68 kDa
• Observed Molecular Weight: 68 kDa
• GenBank Accession Number: NM_003165
• Gene Symbol: STXBP1
• Gene ID (NCBI): 6812
• RRID: AB_10694824
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P61764
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

STXBP1, also named as UNC18A, N-Sec1 and p67 belongs to the STXBP/unc-18/SEC1 family. STXBP1 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. STXBP1 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions. The antibody is specific to STXBP1.