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  • KD/KO Validated

TEAD1 Polyclonal antibody

TEAD1 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 13283-1-AP

Synonyms

AA, NTEF 1, Protein GT IIC, REF1, TCF 13, TCF13, TEA domain family member 1, TEAD 1, TEAD1, TEF 1, TEF1, Transcription factor 13



Tested Applications

Positive WB detected inhuman skeletal muscle tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Product Information

13283-1-AP targets TEAD1 in WB,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TEAD1 fusion protein Ag4082
Full Name TEA domain family member 1 (SV40 transcriptional enhancer factor)
Calculated molecular weight 426 aa, 47, 9 kDa
Observed molecular weight 52 kDa
GenBank accession numberBC026959
Gene symbol TEAD1
Gene ID (NCBI) 7003
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TEAD1 belongs to a protein family that share the TEA/ATTS domain. It acts as a transcriptional factor by binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also it can modulate SV40 late transcription together with large T antigen. The transcriptional activity of TEAD1 required several regions of the proteins , a TBP-associated factors and a limiting transcriptional intermediary factors. TEAD1 also preforms an essential role in the Hippo signaling pathway. TEAD1 regulates gene expression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction. TEAD is preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.

Protocols

Product Specific Protocols
WB protocol for TEAD1 antibody 13283-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Arch Oral Biol

Force-induced decline of TEA domain family member 1 contributes to osteoclastogenesis via regulation of Osteoprotegerin.

Authors - Qian Li
  • KD Validated
humanWB

Oncol Lett

siRNA targeting YAP gene inhibits gastric carcinoma growth and tumor metastasis in SCID mice.

Authors - Zhou Zhou
WB

Oncol Rep

YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis.

Authors - Jian-Jia Cao
humanWB

Biomed Pharmacother

YAP1-TEAD1-Glut1 axis dictates the oncogenic phenotypes of breast cancer cells by modulating glycolysis.

Authors - Chunli Lin
humanWB

Int J Mol Sci

Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.

Authors - Rina Fujiwara-Tani