TEAD1 Polyclonal antibody

• Home
• Products
• Primary Antibodies
• TEAD1 Polyclonal antibody (13283-1-AP)

• Featured Product
• KD/KO Validated

TEAD1 Polyclonal Antibody for WB, ELISA

Cat No. 13283-1-AP Copied!

Publications (12)

Download datasheet

Host / Isotype

Rabbit / IgG

Reactivity

mouse, human and More (1)

Applications

WB, IF, ELISA

Synonyms

AA, NTEF 1, Protein GT IIC, REF1, TCF 13, TCF13, TEA domain family member 1, TEAD 1, TEAD1, TEF 1, TEF1, Transcription factor 13

• 

  WB analysis of BGC-823 using 13283-1-AP

  BGC-823 cells were subjected to SDS PAGE followed by western blot with 13283-1-AP (TEAD1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of A375 using 13283-1-AP

  A375 cells were subjected to SDS PAGE followed by western blot with 13283-1-AP (TEAD1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of A375 using 13283-1-AP

  A375 cells were subjected to SDS PAGE followed by western blot with 13283-1-AP (TEAD1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis using 13283-1-AP

  C2C12 cells were subjected to SDS PAGE followed by western blot with 13283-1-AP (TEAD1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

Able AI

What's the best dilution for TEAD1 in ?

Chat with Able

---

Tested Applications

• Positive WB detected in: BGC-823 cells, A375 cells, C2C12 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

13283-1-AP targets TEAD1 in WB, IF, ELISA applications and shows reactivity with mouse, human samples.

• Tested Reactivity: mouse, human
• Cited Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag4082

  Product name: Recombinant human TEAD1 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-60 aa of BC026959

  Sequence: MLTPSIVYECATRNFQRAPFTIWHFQRMFQPSKGQLFKVLVGFYPNLVEIGKADRGKEDE

• Full Name: TEA domain family member 1 (SV40 transcriptional enhancer factor)
• Calculated Molecular Weight: 426 aa, 47, 9 kDa
• Observed Molecular Weight: 52 kDa
• GenBank Accession Number: BC026959
• Gene Symbol: TEAD1
• Gene ID (NCBI): 7003
• RRID: AB_2287290
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P28347
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TEAD1 belongs to a protein family that share the TEA/ATTS domain. It acts as a transcriptional factor by binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also it can modulate SV40 late transcription together with large T antigen. The transcriptional activity of TEAD1 required several regions of the proteins , a TBP-associated factors and a limiting transcriptional intermediary factors. TEAD1 also preforms an essential role in the Hippo signaling pathway. TEAD1 regulates gene expression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration and epithelial mesenchymal transition induction. TEAD is preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.

Publications

What published studies show

The anti-YAP antibody (Cat# 13283-1-AP) has 12 total citations spanning journals including Cell, MedComm, Adv Sci, Cancer Lett, Int J Mol Sci, Cancers, Oncol Rep, Dig Dis Sci, Biomed Pharmacother, Arch Oral Biol, Prog Orthod, and Oncol Lett. Research fields cover RNA metabolism and stress granules, osteogenic differentiation, bone remodeling, glioma epigenetics, breast cancer (vasculogenic mimicry, glycolysis), renal cell carcinoma, hepatocellular carcinoma ferroptosis, colonic adenoma, and gastric carcinoma metastasis.

Automatically generated from the 12 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	Cell; QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism; Authors - Zhicong Zhao
rat	WB	MedComm (2020); YAP/TEAD1 and β-catenin/LEF1 synergistically induce estrogen receptor α to promote osteogenic differentiation of bone marrow stromal cells; Authors - Peiqi Wang
human	WB	Adv Sci (Weinh); CRISPR/Cas13 sgRNA-Mediated RNA-RNA Interaction Mapping in Live Cells with APOBEC RNA Editing; Authors - Li-Ting Diao
human	WB	Cancer Lett; EGFR/c-myc axis regulates TGFβ/Hippo/Notch pathway via epigenetic silencing miR-524 in gliomas.; Authors - Kai Zhao
rat	WB	Prog Orthod; Mechanosensor YAP mediates bone remodeling via NF-κB p65 induced osteoclastogenesis during orthodontic tooth movement; Authors - Jie Deng
human	WB	Int J Mol Sci; Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.; Authors - Rina Fujiwara-Tani