THSD7A Polyclonal antibody

THSD7A Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, Mouse and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 28524-1-AP

Synonyms

KIAA0960, THSD7A

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Validation Data Gallery

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  WB analysis using 28524-1-AP

  mouse kidney tissue was subjected to SDS PAGE followed by western blot with 28524-1-AP (THSD7A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: mouse kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:600-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

28524-1-AP targets THSD7A in WB, ELISA applications and shows reactivity with Human, Mouse samples.

• Tested Reactivity: Human, Mouse
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: THSD7A fusion protein Ag29107
• Full Name: thrombospondin, type I, domain containing 7A
• Calculated Molecular Weight: 185 kDa
• Observed Molecular Weight: 240-250 kDa
• GenBank Accession Number: NM_015204
• Gene Symbol: THSD7A
• Gene ID (NCBI): 221981
• RRID: AB_2918172
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Thrombospondin type-1 domain-containing protein 7A (THSD7A) is a membrane-associated N-glycoprotein with a molecular weight of 250 kDa, which can be cleaved to release a 210-kDa soluble form (PMID: 22194972; 27214550). THSD7A has a role in angiogenesis. It mediates endothelial cell migration and tube formation (PMID: 2002048). THSD7A has been identified as a second autoantigen involved in adult idiopathic membranous nephropathy in addition to PLA2R1 (PMID: 25394321).

Publications

Species	Application	Title
human	WB	Genomics Proteomics Bioinformatics; The Proteome Landscape of Human Placentas for Monochorionic Twins with Selective Intrauterine Growth Restriction; Authors - Xin-Lu Meng