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TMEM173/STING Monoclonal antibody
TMEM173/STING Monoclonal Antibody for IHC, WB,ELISA
Cat no : 66680-1-Ig
|Positive WB detected in||HSC-T6 cells, HEK-293 cells, HepG2 cells, Jurkat cells|
|Positive IHC detected in||human tonsillitis tissue, human spleen tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:2000-1:10000|
|Immunohistochemistry (IHC)||IHC : 1:500-1:2000|
|Sample-dependent, check data in validation data gallery|
66680-1-Ig targets TMEM173/STING in WB, IHC,ELISA applications and shows reactivity with Human, Rat samples.
|Tested Reactivity||Human, Rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||TMEM173/STING fusion protein Ag20363|
|Full Name||transmembrane protein 173|
|Calculated molecular weight||379 aa, 42 kDa|
|Observed molecular weight||37 kDa|
|GenBank accession number||BC047779|
|Gene ID (NCBI)||340061|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
TMEM173, also named as ERIS, MITA, STING and MPYS, is a facilitator of innate immune signaling that promotes the production of type I IFN (IFN-alpha and IFN-beta). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Staphylococcus aureus Induces IFN-β Production via a CARMA3-Independent Mechanism.
Cell Death Differ
The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson's disease.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Will (Verified Customer) (04-25-2019)
good antibody, will order again