• Featured Product
  • KD/KO Validated

TMPO/LAP2 Polyclonal antibody

TMPO/LAP2 Polyclonal Antibody for IF, IHC, IP, WB, ELISA

Host / Isotype

Rabbit / IgG


human, rat, mouse and More (1)





Cat no : 14651-1-AP


CMD1T, LAP2, LEMD4, PRO0868, Splenin Thymopentin, thymopoietin, Thymopoietin isoform alpha, TMPO, TMPO/LAP2, TP, TP alpha, TP5, TPRP isoform alpha

Tested Applications

Positive WB detected inHEK-293 cells, HSC-T6 cells, HeLa cells, HepG2 cells, MCF-7 cells
Positive IP detected inHeLa cells
Positive IHC detected inhuman breast cancer tissue, human liver tissue, mouse lung tissue, human liver cancer tissue, mouse brain tissue, rat brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHeLa cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14651-1-AP targets TMPO/LAP2 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, rat, mouse samples.

Tested Reactivity human, rat, mouse
Cited Reactivityhuman, mouse, bovine
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TMPO/LAP2 fusion protein Ag6247
Full Name thymopoietin
Calculated Molecular Weight 51 kDa
Observed Molecular Weight 75 kDa, 51 kDa and 39 kDa
GenBank Accession NumberBC053675
Gene Symbol TMPO
Gene ID (NCBI) 7112
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TMPO resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. TMPO gene encodes 3 thymopoietins: alpha (75 kD), beta (51 kD), and gamma (39 kD).


Product Specific Protocols
WB protocol for TMPO/LAP2 antibody 14651-1-APDownload protocol
IHC protocol for TMPO/LAP2 antibody 14651-1-APDownload protocol
IF protocol for TMPO/LAP2 antibody 14651-1-APDownload protocol
IP protocol for TMPO/LAP2 antibody 14651-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Nat Commun

The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus.

Authors - Ying Zhang

J Cell Biol

A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies.

Authors - Tino Pleiner

Sci Rep

MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells.

Authors - Yuhua Fu

J Dairy Sci

Anti-inflammation of epicatechin mediated by TMEM35A and TMPO in bovine mammary epithelial cell line cells and mouse mammary gland.

Authors - Xiao Ma
  • KO Validated

World J Surg Oncol

Depletion of thymopoietin inhibits proliferation and induces cell cycle arrest/apoptosis in glioblastoma cells.

Authors - Lin Zhang
  • KD Validated


Progerin accumulation in nucleus pulposus cells impairs mitochondrial function and induces intervertebral disc degeneration and therapeutic effects of sulforaphane.

Authors - Xiaolong Xu


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Lauren (Verified Customer) (02-20-2020)

Tested fixes include -20'C Methanol for 10 mins, and both 2% and 4% Formaldehyde for 20 mins. We saw a good signal in all three fixes.

  • Applications: Immunofluorescence,
  • Primary Antibody Dilution: 1:100
  • Cell Tissue Type: mIMCD3
TMPO/LAP2 Antibody Immunofluorescence, validation (1:100 dilution) in mIMCD3 (Cat no:14651-1-AP)