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  • KD/KO Validated

TRPC1 Polyclonal antibody

TRPC1 Polyclonal Antibody for WB, IF, FC, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 19482-1-AP


HTRP 1, Transient receptor protein 1, TRP 1, TRP1, TRPC1

Tested Applications

Positive WB detected inPC-3 cells, human brain tissue, human testis tissue, mouse liver tissue, SH-SY5Y cells
Positive IHC detected inhuman brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inPC-12 cells
Positive FC detected inPC-3 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:10-1:100
Flow Cytometry (FC)FC : 0.20 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

19482-1-AP targets TRPC1 in WB, IP, IF, FC, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name transient receptor potential cation channel, subfamily C, member 1
Calculated Molecular Weight 91 kDa
Observed Molecular Weight 90 kDa, 130 kDa
GenBank Accession NumberNM_003304
Gene Symbol TRPC1
Gene ID (NCBI) 7220
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TRPC1, also named as TRP1, belongs to the transient receptor family and STrpC subfamily. TRPC1 is thought to form a receptor-activated non-selective calcium permeant cation channel. It has been reported that the mGluR1 evoked slow EPSC is mediated by the TRPC1 cation channel. It is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.


Product Specific Protocols
WB protocol for TRPC1 antibody 19482-1-APDownload protocol
IHC protocol for TRPC1 antibody 19482-1-APDownload protocol
IF protocol for TRPC1 antibody 19482-1-APDownload protocol
FC protocol for TRPC1 antibody 19482-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cell Res

Direct control of store-operated calcium channels by ultrafast laser.

Authors - Pan Cheng
  • KD Validated

J Neuroinflammation

Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice.

Authors - Shiji Huo

J Biomed Sci

Chemoresistant ovarian cancer enhances its migration abilities by increasing store-operated Ca2+ entry-mediated turnover of focal adhesions.

Authors - Ho-Kai Huang

Sci Rep

Homer binds to Orai1 and TRPC channels in the neointima and regulates vascular smooth muscle cell migration and proliferation.

Authors - Shuping Jia

J Biochem Mol Toxicol

Galectin-3 mediates pulmonary vascular endothelial cell dynamics via TRPC1/4 under acute hypoxia.

Authors - Yumei Li

Int J Mol Sci

STIM1 Knockout Enhances PDGF-Mediated Ca2+ Signaling through Upregulation of the PDGFR⁻PLCγ⁻STIM2 Cascade.

Authors - Tzu-Yu Huang