TRPC1 Polyclonal antibody

TRPC1 Polyclonal Antibody for FC, IF, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, FC,ELISA

Conjugate

Unconjugated

Cat no : 19482-1-AP

Synonyms

HTRP 1, Transient receptor protein 1, TRP 1, TRP1, TRPC1



Tested Applications

Positive WB detected inPC-3 cells, human brain tissue, human testis tissue, mouse liver tissue, SH-SY5Y cells
Positive IF detected inPC-12 cells
Positive FC detected inPC-3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)IF : 1:10-1:100
Sample-dependent, check data in validation data gallery

Product Information

19482-1-AP targets TRPC1 in WB, IF, FC,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name transient receptor potential cation channel, subfamily C, member 1
Calculated molecular weight 91 kDa
Observed molecular weight 90 kDa, 130 kDa
GenBank accession numberNM_003304
Gene symbol TRPC1
Gene ID (NCBI) 7220
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

TRPC1, also named as TRP1, belongs to the transient receptor family and STrpC subfamily. TRPC1 is thought to form a receptor-activated non-selective calcium permeant cation channel. It has been reported that the mGluR1 evoked slow EPSC is mediated by the TRPC1 cation channel. It is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.

Protocols

Product Specific Protocols
WB protocol for TRPC1 antibody 19482-1-APDownload protocol
IF protocol for TRPC1 antibody 19482-1-APDownload protocol
FC protocol for TRPC1 antibody 19482-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

EBioMedicine

FUN14 domain-containing 1 promotes breast cancer proliferation and migration by activating calcium-NFATC1-BMI1 axis.

Authors - Lianpin Wu
mouseWB

Cell Physiol Biochem

SGK3 regulates Ca(2+) entry and migration of dendritic cells.

Authors - Schmid Evi E
mouseWB

Int J Mol Sci

STIM1 Knockout Enhances PDGF-Mediated Ca2+ Signaling through Upregulation of the PDGFR⁻PLCγ⁻STIM2 Cascade.

Authors - Tzu-Yu Huang
ratWB

J Biochem Mol Toxicol

Galectin-3 mediates pulmonary vascular endothelial cell dynamics via TRPC1/4 under acute hypoxia.

Authors - Yumei Li
ratWB

Sci Rep

Homer binds to Orai1 and TRPC channels in the neointima and regulates vascular smooth muscle cell migration and proliferation.

Authors - Shuping Jia
humanWB

Cell Res

Direct control of store-operated calcium channels by ultrafast laser.

Authors - Pan Cheng
  • KD Validated