Anti-Human TRPV2 Rabbit Recombinant Antibody

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  FC experiment of CHO using 98654-2-RR

  1x10^6 CHO cells or TRPV2 transfected CHO cells were surface stained with 0.25 ug Anti-Human TRPV2 Rabbit RecAb (98654-2-RR, Clone: 251093A1) and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed.

• 

  FC experiment of CHO using 98654-2-RR

  1x10^6 CHO cells(left) or TRPV2 transfected CHO cells(right) were surface stained with 0.25 ug Anti-Human TRPV2 Rabbit RecAb (98654-2-RR, Clone: 251093A1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and CoraLite647-conjugated F(ab')2 Fragment Donkey Anti-Rabbit IgG (H+L) (SA00014-7). Cells were not fixed.

TRPV2 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98654-2-RR

Clone No.251093A1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

Osm 9 like TRP channel 2, Osm-9-like TRP channel 2, OTRPC2, Vanilloid receptor-like protein 1, VRL

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Tested Applications

• Positive FC detected in: Transfected CHO cells

Recommended dilution

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

98654-2-RR targets TRPV2 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: transient receptor potential cation channel, subfamily V, member 2
• Calculated Molecular Weight: 764 aa, 86 kDa
• GenBank Accession Number: BC018926
• Gene Symbol: TRPV2
• Gene ID (NCBI): 51393
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9Y5S1
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

Transient receptor potential vanilloid 2 (TRPV2), also name as VRL-1, plays a critical role in neuronal development, cardiac function, immunity, and cancer (PMID: 31566564). It has been found to play an essential role in sustained intracellular Ca2+ concentration increase (PMID: 31857697). It's reported that TRPV2 is activated by high temperatures, with a threshold of around 52℃ (PMID: 10201375).