VDAC1/Porin Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66345-1-Ig |CloneNo.: 1E2C7

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Freight/Packing

Con: 64 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
RAW 264.7 cells, HEK-293 cells, Jurkat cells, K-562 cells, C6 cells, ROS1728 cells, NIH/3T3 cells, 3T3-L1 cells

Positive IHC detected in:
human heart tissue, human skeletal muscle tissue

Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG3

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
voltage-dependent anion channel 1

Calculated molecular weight:
31 kDa

Observed molecular weight:
35-37 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
VDAC1

Synonyms
hVDAC1, Plasmalemmal porin, Porin, PORIN 31 HL, Porin 31HL, Porin 31HM, VDAC, VDAC 1, VDAC1
Background

VDAC1, also named as VDAC, Porin 31HM, Porin 31HL and Plasmalemmal porin, belongs to the eukaryotic mitochondrial porin family. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV, to form a channel through the mitochondrial outer membrane and also the plasma membrane. Unlike other membrane transport proteins, porins are large enough to allow passive diffusion.


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