XBP1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 25997-1-AP

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Freight/Packing

Con: 61 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
rat spleen tissue, mouse spleen tissue, rat spleen tissue

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human colon cancer tissue, human liver cancer tissue, mouse liver tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
X-box binding protein 1

Calculated molecular weight:
261aa,29 kDa

Observed molecular weight:
32 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
XBP1

Synonyms
TREB5, X box binding protein 1, XBP 1, XBP1, XBP2
Background

X-box-binding protein 1 (XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa.


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