ZBTB7A Polyclonal antibody
ZBTB7A Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 18700-1-AP
Synonyms
Validation Data Gallery
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 1 publications below |
Product Information
18700-1-AP targets ZBTB7A in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide |
| Full Name | zinc finger and BTB domain containing 7A |
| Calculated Molecular Weight | 61 kDa |
| GenBank Accession Number | BC113511 |
| Gene Symbol | ZBTB7A |
| Gene ID (NCBI) | 51341 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
ZBTB7A, also named as LRF, FBI1, FBI-1, ZBTB7, ZNF857A, pokemon and DKFZp547O146, plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals. ZBTB7A may be involved in transcriptional regulation. It enhances transcription of the NF-kappaB-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-kappaB. ZBTB7A is widely expressed in normal thymus and it is aberrantly overexpressed in human cancers. Results suggest that this protein can specifically stimulate Tat-activated HIV-1 transcription.
Publications
| Species | Application | Title |
|---|---|---|
Biomed Res Int Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1.
|
