nNOS Polyclonal antibody
nNOS Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat and More (1)
Cat no : 18984-1-AP
Validation Data Gallery
|Positive IHC detected in||mouse heart tissue, mouse kidney tissue, rat testis tissue, mouse brain tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
18984-1-AP targets nNOS in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||mouse, rat, canine|
|Host / Isotype||Rabbit / IgG|
|Full Name||nitric oxide synthase 1 (neuronal)|
|Calculated molecular weight||161 kDa|
|GenBank accession number||NM_000620|
|Gene ID (NCBI)||4842|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
nNOS belongs to the NOS family. nNOS produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. nNOS is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in nNOS gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1 (IHPS1).The antibody can recognize isoform 1,2,4 of nNOS.
|Product Specific Protocols|
|IHC protocol for nNOS antibody 18984-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Exp Eye Res
Altered transsulfuration pathway enzymes and redox homeostasis in inherited retinal degenerative diseases.
Acta Pharmacol Sin
Neuroprotective effects of scutellarin on rat neuronal damage induced by cerebral ischemia/reperfusion.
ACS Chem Neurosci
Antidepressant-like Effect of Merazin Hydrate Depends on NO/ERK by Suppressing Its Downstream NF-κB or Nonactivating CREB/BDNF in Mouse Hippocampus.