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Product Information
60089-1-Ig targets phospho-RCC1(Ser11) in ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen |
peptide Predict reactive species |
| Full Name | regulator of chromosome condensation 1 |
| Calculated Molecular Weight | 48 kDa |
| Observed Molecular Weight | 47 kDa |
| GenBank Accession Number | NM_001048194 |
| Gene Symbol | RCC1 |
| Gene ID (NCBI) | 1104 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P18754 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a mouse monoclonal antibody raised against human phospho-CHC1(Ser11) antigen.
